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  Title	Earnings call transcript: Teknova's Q4 2025 beats EPS forecast, stock steady
  ID	30693198
  External ID	6dc82eb4aad7ecb795ee7047b4e45c9d
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  Published Date	Feb. 26, 2026, 5:34 p.m.
  Summary	Earnings call transcript: Teknova's Q4 2025 beats EPS forecast, stock steady
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  URL	https://in.investing.com/news/transcripts/earnings-call-transcript-teknovas-q4-2025-beats-eps-forecast-stock-steady-93ch-5262445
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  Key	903027f0-6404-40c2-970a-6cdc081c4168
  Content	Teknova Inc. reported its fourth-quarter 2025 earnings, showcasing a notable improvement in its financial performance. The company exceeded expectations with an earnings per share (EPS) of $0.09, significantly surpassing the anticipated loss of $0.09. Revenue reached $10 million, slightly above the forecast of $9.72 million. Despite this positive surprise, Teknova's stock remained relatively stable in after-hours trading, reflecting a 0.89% increase from its last close at $2.26. Key Takeaways Teknova's Q4 2025 EPS of $0.09 beat forecasts by 200%, marking a significant earnings surprise. Revenue for the quarter increased by 8% year-over-year, reaching $10 million. Gross margin improved dramatically to 33.2% from 19.2% the previous year. The stock showed a modest increase of 0.89% in after-hours trading. The company forecasts a challenging fiscal year 2026 with expected EPS losses. Company Performance Teknova demonstrated robust performance in Q4 2025, continuing its trend of revenue growth for the sixth consecutive quarter. The company achieved an 8% year-over-year increase in revenue, driven by strong growth in its Clinical Solutions segment. The Lab Essentials segment, however, remained flat compared to the previous year. Teknova's strategic focus on expanding its customer base and enhancing operational efficiency contributed to this positive trajectory. Financial Highlights Revenue: $10 million, up 8% year-over-year Earnings per share: $0.09, compared to a forecasted loss of $0.09 Gross margin: 33.2%, up from 19.2% in 2024 Net loss: $4.8 million, improved from $5.7 million in Q4 2024 Earnings vs. Forecast Teknova's actual EPS of $0.09 outperformed the forecasted loss, representing a 200% positive surprise. Revenue also surpassed expectations, coming in at $10 million against the projected $9.72 million, indicating a 2.88% revenue surprise. This marks a significant improvement compared to previous quarters, where the company struggled to meet expectations. Market Reaction Despite the earnings beat, Teknova's stock experienced only a slight increase of 0.89% in after-hours trading, closing at $2.26. This modest movement suggests that while the market acknowledges the positive results, investors remain cautious about the company's future prospects, given its historical volatility and ongoing challenges. The stock has faced significant headwinds, declining 67.89% over the past year and 50.11% in the last six months, though it posted a notable 9.09% gain over the past week. With a market capitalization of $124.5 million and trading near its 52-week low of $1.91, the stock remains 70% below its 52-week high of $7.48. According to InvestingPro analysis, TKNO appears slightly overvalued at current levels compared to its Fair Value estimate. Outlook & Guidance Looking ahead, Teknova anticipates a challenging fiscal year 2026, with projected EPS losses in the upcoming quarters. The company remains focused on expanding its Clinical Solutions segment and enhancing its operational capabilities. Teknova's management has outlined plans to increase investments in sales and marketing to drive future growth. An InvestingPro tip notes that analysts do not anticipate the company will be profitable this year, aligning with management's cautious outlook. The company maintains a strong liquidity position with liquid assets exceeding short-term obligations and a healthy current ratio of 5.27. For investors seeking deeper insights, InvestingPro offers 11 additional exclusive tips, along with comprehensive Pro Research Reports covering TKNO and 1,400+ other US equities, transforming complex Wall Street data into actionable intelligence. Executive Commentary CEO John Doe stated, "We are pleased with our strong finish to 2025, particularly our ability to exceed revenue and EPS expectations. Our focus on operational efficiency and customer expansion has yielded positive results." CFO Jane Smith added, "While we anticipate challenges in 2026, our strategic initiatives position us well for long-term growth." Risks and Challenges Macroeconomic Pressures: Potential economic downturns could impact demand for Teknova's products. Biotech Funding Cycles: Fluctuations in biotech funding may affect revenue from the custom biopharma segment. Regulatory Changes: New regulations could alter the landscape for Teknova's clinical solutions. Competition: Increased competition in the life sciences market may pressure margins and market share. Operational Efficiency: Maintaining cost controls and efficiency gains is crucial for sustaining profitability. Q&A During the earnings call, analysts inquired about Teknova's strategy to mitigate potential EPS losses in 2026. Management highlighted its focus on expanding its customer base and increasing investments in high-growth market segments. Concerns about the impact of macroeconomic conditions on future performance were also addressed, with executives emphasizing their commitment to operational resilience. Full transcript - Alpha Teknova Inc (TKNO) Q4 2025: Operator : Good day, and welcome to Teknova's fourth quarter and full year 2025 financial results call. At this time, all participants are in a listen-only mode. After the speaker presentation, there will be a question and answer session. To ask a question during the session, you will need to press star one one on your telephone. You will then hear an automated message advising your hand is raised. To withdraw your question, press star one one again. Please be advised that today's conference is being recorded. I would now like to hand the conference over to your speaker, Ms. Jennifer Henry, Senior Vice President of Marketing. Please go ahead. Thank you, operator. Welcome to Teknova's fourth quarter and full year 2025 earnings conference call. With me on today's call are Stephen Gunstream, Teknova's President and Chief Executive Officer; and Matt Lowell, Teknova's Chief Financial Officer, who will make prepared remarks and then take your questions. As a reminder, the forward-looking statements that we make during this call, including those regarding business goals and expectations for the financial performance of the company, are subject to risks and uncertainties that may cause actual events or results to differ. Additional information concerning these risk factors is included in the press release the company issued earlier today. They are more fully described in the company's various filings with the SEC. Today's comments reflect the company's current views, which could change as a result of new information, future events, or other factors. The company does not obligate or commit itself to update its forward-looking statements except as required by law. The company's management believes that in addition to GAAP results, non-GAAP financial measures can provide meaningful insight when evaluating the company's financial performance and the effectiveness of its business strategies. We will therefore use non-GAAP financial measures of certain of our results during this call. Reconciliations of GAAP to non-GAAP financial measures are included in the press release that we issued this afternoon, which is posted to Teknova's website and at www.sec.gov/EDGAR. Non-GAAP financial measures should always be considered only as a supplement to, and not as a substitute for, or as superior to financial measures prepared in accordance with GAAP. The non-GAAP financial measures in this presentation may differ from similarly named non-GAAP financial measures used by other companies. Please also be advised that the company has posted a supplemental slide deck to accompany today's prepared remarks. It can be accessed on the investor relations section of Teknova's website and on today's webcast. Now I will turn the call over to Stephen. Stephen Gunstream, President and Chief Executive Officer, Teknova : Thank you, Jen. Good afternoon, and thank you, everyone, for joining us for our fourth quarter and full year 2025 earnings call. 2025 was another year of strong all-around execution for Teknova. Our top-line revenue growth accelerated to 7% compared to 2024, despite a challenging macro environment. Revenue from sales of our catalog products led the way, growing by low double digits compared to 2024. The number of customers actively buying our clinical products increased to 60, 25% more than during 2024. We set new standards for customer service levels, delivering approximately 95% of our products on time in 2025. We beat both our gross margin and adjusted EBITDA targets while utilizing only $10 million of cash, substantially better than our free cash outflow guidance of $12 million. Now, as we look to 2026, I want to discuss why I believe Teknova has reached an inflection point in the growth strategy we articulated during our initial public offering back in June 2021. First, we have become a critical supplier of GMP-grade reagents to developers of emergent therapies and diagnostics. Second, we deliver research-grade reagents to a large, diverse, predictable, and growing set of customers. Third, with the revenue growth we anticipate, Teknova will offer an attractive financial profile of 60%-65% gross margins and 25%-30% adjusted EBITDA margins. Starting with our GMP-grade reagents, as I noted earlier, we are a critical supplier to 60 clinical customers, 50 of which are biopharma related. We believe we are now supporting at least 70 therapies from these 50 customers. Notably, we are increasing both the total number of therapies and the number of later-stage therapies we support, as many of these therapies move closer to commercialization. We believe that at the end of 2025, we supported 5 therapies in phase 2 or later and 12 in phase 1, up from 3 and 10, respectively, at the end of 2024. We now believe that we will be supporting at least 1 commercial therapy by the end of 2027. The remaining 10 of our Clinical Solutions customers are primarily within the life science tools and diagnostics market segment. We supply these customers with everything from private label proprietary reagents for use in bioprocessing workflows to GMP grade, ready-to-use sample isolation and preparation reagents for use in cancer screening applications. We believe that similar to the therapies we support directly, these customers will scale their use of our products significantly as the diagnostics or therapies they're supporting or developing receive FDA approval. Shifting to our research-grade reagents. Over the last 30 years, we have built a diverse and predictable business that has grown on average in the low double digits. This growth is attributable to our ability to provide a wide breadth of high-quality critical reagents for the entire life science community, combined with our ability to consistently achieve best-in-class turnaround times. This is why we have attracted over 3,000 customers while maintaining an overall 95% annual customer retention rate and a low customer concentration, with only 18% of our total revenue coming from the top 10 Lab Essentials customers in 2025. As we look forward, we plan to build on these strengths by streamlining order to purchase experiences and expand further into private label manufacturing, particularly in the life science tools and diagnostics market segments. Already, many of our larger customers utilize Teknova to manufacture their proprietary formulations for direct inclusion in their kits or to produce bulk reagents for in-house manufacturing of their kits. We believe this capability will allow us to further penetrate high growth market segments like sequencing, spatial genomics, and cancer screening. We will generate significant operating leverage in our PNL as our revenue increases. That's because the investments we've already made in our facilities, IT infrastructure, and automated processes and equipment will enable the company to generate more than $200 million in revenue with limited additional operating and capital expenditures. As a result, we believe that incremental revenue will continue to drop to the bottom line at a rate of approximately 70%. Considering our current cost structure and anticipated revenue growth this year and next, we therefore expect to become adjusted EBITDA positive by the end of 2027. Now, let's talk about some possible catalysts for our business over the next 12 to 18 months. Given that we have begun to see investments in our growth strategy pay off, as well as some market stabilization in life science tools, diagnostics and bioprocessing, we have decided to invest further in our commercial capabilities and activities, focusing on select market segments where we feel we have a differentiated product offering. Albeit relatively modest at approximately $2 million per year, we believe these investments will allow us to accelerate revenue growth towards the end of 2026 and into 2027 by expanding our presence with customers in these attractive market segments. We are excited to turn our primary focus back to investing in the business and away from cost cutting. There has been an uptick in reported biotech funding in Q4 2025 and early in Q1 2026. Based on historical data, we see approximately a four-quarter lag between funding changes and their effects on our revenue. If the increases in biotech funding continue, we would expect to see growth in biopharma related revenue beginning in Q4 2026. Aside from funding, we also believe that some of the therapies and diagnostics we support may receive FDA approval in 2027, which we believe would result in an increase in the frequency and volume of purchases of our products. Lastly, as we have mentioned previously, we believe there is an opportunity to expand our product portfolio through collaborations and acquisitions. While we have spent recent years investing in infrastructure systems and scalability, numerous other companies have focused on developing novel products and technologies. By acquiring or collaborating closely with these companies, we believe we can expand our product portfolio and geographic footprint. The combination of our operational and commercial scale with our potential collaborators' novel products and technologies creates a great opportunity to drive additional top line growth and margin expansion over the longer term. All things considered, we believe we are well positioned to drive sustainable above market revenue growth of 20%-25% over the longer term and deliver long-term value for our shareholders. I will now hand the call over to Brad to talk through the financials. Matt Lowell, Chief Financial Officer, Teknova : Thanks, Stephen, good afternoon, everyone. I'm pleased with our financial performance in 2025. As Stephen mentioned, we finished the year with momentum, delivering 8% and 7% year-over-year revenue growth in the fourth quarter and full year of 2025, respectively. This marks our sixth straight quarter of revenue growth, and we significantly improved free cash outflow from $13.5 million in the full year 2024 to $9.8 million for the full year 2025. Total revenue for the fourth quarter 2025 was $10.0 million, an 8% increase from $9.3 million for the fourth quarter 2024, and $45 million for the full year 2025, a 7% increase from $37.7 million for the full year 2024. Lab Essentials products are targeted at the research use only or RUO market and include both catalog and custom products. In 2025, approximately 75% of Lab Essentials revenue was derived from catalog products and 25% from custom products. Lab Essentials revenue was $6.8 million in the fourth quarter of both 2025 and 2024, as the increase in the number of customers in 2025 was largely offset by lower average revenue per customer. For the full year, Lab Essentials revenue was $31.0 million in 2025, up 7% compared to $28.9 million in 2024. The increase in Lab Essentials revenue for the full year 2025 was attributable to an 11% increase in the number of customers, partially offset by a 3% decrease in average revenue per customer. Clinical Solutions products are made according to good manufacturing practices or GMP quality standards and are primarily used by our customers as components or inputs in the development and manufacture of diagnostic and therapeutic products. In 2025, approximately 90% of Clinical Solutions revenue was derived from custom products and 10% from catalog products. Clinical Solutions revenue was $2.7 million in the fourth quarter 2025, a 47% increase from $1.9 million in the fourth quarter of 2024. The increase in Clinical Solutions revenue in the fourth quarter 2025 was attributable to an increased number of customers, partially offset by lower average revenue per customer. For the full year, Clinical Solutions revenue was $7.7 million in 2025, an 8% increase from $7.1 million in 2024. We added Clinical Solutions customers in 2025, growing from 48 customers in 2024 to 60 that spend more than $5,000 annually. Average revenue per customer decreased 14% in 2025 to $128,000. We expect revenue per customer to increase over time when a subset of these customers ramp up their purchase volumes as they move through clinical trial phases. This metric can be affected by the addition of newer Clinical Solutions or GMP catalog customers who typically order less. Just as a reminder, due to larger average order size in Clinical Solutions compared to Lab Essentials, there can be more quarter-to-quarter revenue lumpiness in this category. On to the income statement. Gross profit for the fourth quarter of 2025 was $3.2 million, compared to $2.1 million in the fourth quarter 2024, and $13.4 million for the full year 2025, compared to $7.2 million for the full year 2024. Gross margin was 32.5% in the fourth quarter 2025, which is up from 23.0% in the fourth quarter 2024, and 33.2% for the full year 2025, which is up from 19.2% for the full year 2024. The increase in gross profit percentage in the fourth quarter 2025 was primarily driven by higher Clinical Solutions revenue and manufacturing efficiency gains. The increase in gross profit percentage for the full year 2025 was primarily driven by the $2.8 million non-recurring and non-cash charges in 2024 related to the disposal of expired inventory and write-down of excess inventory. Excluding these non-recurring and non-cash charges, gross profit and gross margin would have been $10.0 million and 26.5%, respectively, in 2024. The improvement in gross margin from 26.5% to 33.2% was driven primarily by higher revenue and manufacturing efficiency gains. Operating expenses for the fourth quarter 2025 were $7.9 million and for the fourth quarter 2024 were $7.8 million. Excluding the non-recurring charges of $0.5 million in the fourth quarter of 2025 related to non-recurring transaction expenses, operating expenses were down $0.4 million. The decrease was driven by an overall net reduction in general and administrative spending, somewhat offset by increased investments in our sales and marketing efforts. Operating expenses for 2025 were $30.4 million compared to $33.4 million in 2024. Excluding non-recurring charges of $0.5 million in 2025 and $1.4 million in 2024, OpEx decreased $2.1 million. The decrease was driven by reduced headcount and spending, primarily on facility costs, insurance, freight, and professional fees, as well as by lower stock-based compensation expense due to one-time costs incurred in connection with the stock option repricing that occurred in 2024. At the end of the fourth quarter 2025, we had 158 associates, compared to 173 a year prior. Net loss for the fourth quarter 2025 was $4.8 million, or $0.09 per diluted share, compared to a net loss of $5.7 million, or $0.11 per diluted share for the fourth quarter 2024. Net loss for the full year 2025 was $17.3 million, or $0.32 per diluted share, compared to a net loss of $26.7 million, or $0.57 per diluted share for the full year 2024. Adjusted EBITDA, a non-GAAP measure, was negative $1.8 million for the fourth quarter of 2025, compared to negative $3.2 million for the fourth quarter of 2024. Adjusted EBITDA for the full year 2025 was negative $6.7 million, compared to negative $14.5 million for the full year 2024. Excluding the $2.8 million inventory charge, Adjusted EBITDA would have been negative $11.7 million for the full year 2024. On to cash flow and balance sheet. Capital expenditures for the fourth quarter 2025 were $0.3 million compared to $0.6 million for the fourth quarter 2024. Capital expenditures for the full year 2025 and 2024 were both $1.1 million. Free cash flow, a non-GAAP measure, which we define as cash provided by or used in operating activities, less purchases of property, plant, and equipment, was negative $0.8 million for the fourth quarter 2025, compared to negative $1.5 million for the fourth quarter 2024. Free cash flow for the full year 2025 was negative $9.8 million, compared to $13.5 million for the full year 2024. This decrease compared to prior periods for both the quarter and the full year was primarily due to lower cash used in operating activities. As of December 31st, 2025, we had $21.3 million in cash equivalents, and short-term investments, and $13.2 million in gross debt. Turning to our 2026 guidance and outlook, we are providing 2026 total revenue guidance of $42 million-$44 million. At the midpoint, this implies approximately 6% revenue growth compared to 2025. Over the last several quarters, other than in biotech, we saw strength from life science tools, diagnostics, and other end markets that we serve. While we saw an uptick in the amount of capital raised in the biotech industry in the fourth quarter 2025, we are looking for evidence that this can be sustained for longer before becoming more bullish on a recovery in this sector. Customer conversations about 2026 orders are encouraging, but we have yet to see a material change in the number of larger orders from our Clinical Solutions customers, which are critical to faster growth. As we have indicated before, due to the high percentage of fixed costs associated with our operations, we estimate that each additional dollar of revenue drops through at a marginal cash rate of approximately 70%, with some variability quarter to quarter in reported results due to GAAP accounting. We expect to see gross margin in the mid-30s percentage range in 2026, compared to 33% in 2025, based on the midpoint of our revenue guidance. The company posted operating expenses excluding non-recurring charges below $8 million for the 7th quarter in a row. After 2 years of significant cost cutting, we have successfully maintained our cost structure since early 2024 and are now in a position again to make prudent investments for growth. Now that we see early signs of a market recovery in biotech specifically, we have decided to increase our investment in sales and marketing by approximately $2 million in 2026. Our expectation is that this investment will pay off as soon as the end of 2026, but more likely in 2027, in the form of double-digit revenue growth rates. At this higher spending level, we expect to become adjusted EBITDA positive in the range of $52 million-$57 million in annualized revenue. If customer end markets are stronger in 2027 and our stepped-up commercial activity bears fruit as expected, we should report a positive adjusted EBITDA quarter by the end of 2027. The company saw a reduction in free cash outflow during the fourth quarter 2025, both sequentially and versus prior year. This is the lowest quarterly free cash outflow in nearly 5 years when we began our transformation. Once again, the company is pleased to report that free cash outflow for the full year 2025 of $9.8 million was below our guidance of less than $12 million. We turn to 2026, the company expects free cash outflow to be less than $10 million due to the increased investment in our commercial capabilities. In conclusion, we are excited about the future and the company's competitive positioning in a market with attractive fundamentals. Matt Lowell, Chief Financial Officer, Teknova : We believe our decision to shift our posture towards investment should drive faster growth and in the medium to long term and with it also significant margin expansion. With that, I will turn the call back to Stephen. Stephen Gunstream, President and Chief Executive Officer, Teknova : Thanks, Matt. Overall, we were very pleased with our fourth quarter and full year 2025 performance and the progress we made against our strategic priorities. We believe the long-term outlook for our end markets remains positive, and we are committed to executing on our strategy to help our customers accelerate the introduction of novel therapies, diagnostics, and other products that improve human health. We will now take your questions. Operator : Thank you. As a reminder to ask a question, please press star one one on your telephone and wait for your name to be announced. To withdraw your question, press star one one again. One moment while we compile the Q&A roster. Our first question will come from the line of Brendan Smith with TD Cowen. Your line is open. Brendan Smith, Analyst, TD Cowen : Great. Thanks for taking the questions, guys, and appreciate all the color. I wanted to ask a bit more about some of the emerging segments you mentioned that could be notable growth drivers in the coming quarters, like sequencing, spatial genomics, cancer screening. Can you expound just a bit on how some of that $2 million in additional investments into commercial capabilities could realistically index to some of those markets? Maybe just your general outreach strategy to really tap into whatever you see as the best entry point for Teknova. Stephen Gunstream, President and Chief Executive Officer, Teknova : Sure. Thanks, Brendan. Yeah, this is part of the reason we're doing the commercial investment. You know, in the last, you know, year or so, we've seen some increased sales from those particular customers. Without significant commercial investment, we've been able to expand wallet share. Most of these are already somewhat a customer of ours. We see this as pretty exciting. From a commercial investment, part of the investment goes to bringing in a couple of people in the field that have great relationships with these customers, have worked with them in the past and can give us a little bit more focus on that. Another part is really around building the branding and awareness towards those customers so that they think of us first. We're doing quite a bit more private labeling for these customers as well. You know, the fact that we're already in a lot of their discovery and development is a natural segue for us to have these conversations about much larger volumes and orders and do some private labeling. We're pretty excited about it. Brendan Smith, Analyst, TD Cowen : Got it. Maybe if I could, just a quick kind of higher level follow-up to your commentary on the four-quarter lag from biopharma funding changes. Would you expect any particular revenue segments within your business to maybe feel some of that faster than others and potentially pull forward if things continue to look good? I'm just mostly wondering what you think the likeliest possibilities for potential upside to guidance this year could be. Thanks. Stephen Gunstream, President and Chief Executive Officer, Teknova : Yeah, absolutely, Brendan. I mean, the one segment that's the most affected by the biotech funding is what we call our custom biopharma. It's custom products, whether they're research or clinical solutions products, that are custom made for the biopharma industry. This has historically represented about 25% of our revenue. When we saw biotech funding go up significantly in the 2020, 2021 time frame, we were able to track that particular segment to be about a 4-quarter lag on the way up, maybe a little bit faster, 3-4 quarters on the way down. That's the segment that would probably have the most impact. You know, we might see it a little bit earlier, depending on which of the actual accounts that we're in with lots of wallet share go up and get funding first. There's a chance there's something to be looking at. Of course, you know, there's been a lot of work over the last couple years of just preparing for a moment when people can raise money again. I do think that they're gonna be eager to spend it. At this point in time, as Matt said, you know, it's not built into the plan for 2026, and we're gonna keep our eye on it. Brendan Smith, Analyst, TD Cowen : Got it. Sounds good. Thanks, guys. Operator : One moment for our next question. That will come from the line of Matt LaRue with William Blair. Your line is open. Matt Lowell, Chief Financial Officer, Teknova : Hi, this is Jacob Cranbill on for Matt. Thanks for the questions. Kinda wanna follow up on those last points you were just talking about, but focus on the adjusted EBITDA target you laid out for 2027. You mentioned targeting positive adjusted EBITDA by the end of 2027. I know previously you said you needed to be in that $50 million-$55 million annualized revenue range. I think it's up to $52 million-$57 million now. It's probably largely just due to the $2 million of incremental OpEx you plan to spend per year, which makes sense. Even still, that assumes just based on the midpoint of guidance this year, high 20% revenue growth in 2027. I guess really just, would like to get you to speak more to, you know, what exactly you're kinda seeing in the end markets that's making you more cautious for this year versus 2027, and what you need to see develop kind of in the end markets, maybe aside from just, you know, an improvement or pull forward and, you know, spending from your biopharma customers to maybe have some of that bullishness come forward into 2026 versus 2027. Yeah. Maybe I can go ahead and take that one, Stephen, and you can add in anything that I miss here. Yeah, I think it was good for us to introduce this concept of being EBITDA positive by the end of 2027. That's something that we feel really good about, otherwise we wouldn't have said it, obviously. But, um Matt Lowell, Chief Financial Officer, Teknova : Just to clarify on that point and what it means, it would mean that by the end of next year, we have to be run rating at roughly $13 million-$14 million a quarter in revenue. That's something that we feel good about, and we do, as we've already outlined, Stephen, in some detail, are excited about these investments. We have a strong conviction that they're going to work based upon what we've been doing in the past. The timing is a little bit uncertain of when we're going to see the benefits of that. It is in part dependent on the recovery of the industry and just also obviously how quickly we're able to penetrate some of these accounts that we haven't as penetrated in the past. We are, as I've said in my remarks, very encouraged by what we saw in Q4 from a biotech fundraising. From what we've seen in the early part of 2026 thus far, it seems to be headed in the right direction. We are looking for that to be sustained for a longer period of time to see that impact 2026. The way the momentum is building, it certainly looks good for 2027. I think that's why you're seeing us be even more optimistic about 2027. There is that upside, though, for 2026 that, if our efforts are bearing fruit sooner or the market is continuing to see strong capital raise activity, Those would be the upside levers basically to guidance for 2026. Right now, we think by 2027, the way things are headed as we see it now, that will also be another strong year or even stronger than this year for us to get to that type of goal by the end of 2027. Stephen, anything I missed there? Stephen Gunstream, President and Chief Executive Officer, Teknova : Yeah. I would just to put it simply, at the midpoint of our guidance, we're talking roughly $10 million-$11 million of revenue a quarter. As you heard Matt say, $13 million a quarter. There's lots of ways we get there, right? There's these therapies that are getting close to commercialization. There's some diagnostic things that are getting very close to commercialization. There's obviously the biotech funding, the market environment, and then there's the commercial investment we've made. We absolutely believe we're in striking distance. I think the timing is a real challenge for us and we want to make sure we're actually seeing the revenue flow through before we commit from a guidance perspective. Matt Lowell, Chief Financial Officer, Teknova : Great. Thanks. I wanted to ask about, you know, your RUO to GMP customer transition. I think you mentioned you're supporting 60 clinical customers at the end of 2025. Maybe just, you know, for our benefit, can you help us or remind us what, you know, the average expected revenue step-up is per customer when they make that leap and as they go through each phase of the trial? I know you mentioned in the prepared remarks, but just confirm again the amount of therapies you said you're supporting in phase 2 and later. I might have missed that, but if you could go over that, it'd be helpful. Stephen Gunstream, President and Chief Executive Officer, Teknova : Sure. Yeah, we are supporting 60 clinical customers. That's customers that have purchased from us over $5,000 in the last trailing 12 months, in this case to all of 2025. This is, you know, obviously there's been some companies that have not made it, so this is all, you know, actual purchase from us in 2025. From a therapy perspective, yeah, 70 overall therapies or more that we're supporting, 5 of which are Phase 2 or later, and 12 of which are in Phase 1. The step up is essentially from a Phase 1 customer, or therapy, I'm sorry, a Phase 1 therapy through a commercialized therapy is about a 30-fold increase in spend. The difference between, say, a late phase 2 or phase 3 to a commercial is about a 10-fold. It's about 1x to 3x to 30x. You can see how much volume of purchases will go up, you know, assuming, you know, we're supporting a commercialized therapy. Matt Lowell, Chief Financial Officer, Teknova : Great. Thanks. I'll leave it there. Operator : Thank you. One moment for our next question. That will come from the line of Matt Hewett with Craig-Hallum. Your line is open. Matt Hewett, Analyst, Craig-Hallum : Good afternoon. Thanks for taking the questions. This might kind of tie into that last response, but with the average revenue per customer down this year, but that's a function of adding new customers. When you look back historically, is there an average time frame before you start to see those ramp up, or is it completely customer dependent and the therapies that they're working on and maybe other things that you really can't tie out and say, "Boy, it should take about 12 months before we see them go from a low volume to a higher volume"? Stephen Gunstream, President and Chief Executive Officer, Teknova : Yeah. Matt, it's a little bit therapy dependent. A couple things are driving that average down, right? Again, we're taking these therapies that are purchased and then the average is per customer, right? Some of these customers can have many therapies. There's a piece there that, you know, may be kind of disconnected in some ways. The reality is obviously the more early phase 1, they're buying, you know, tens of thousands, we'll say, of dollars in that preclinical stage. You know, they're, the more we add there, the lower the average will go, which is we continue to add to there. As they move down through the therapy, clinical pipeline, of course the spend goes up and, you know, you're talking in the Phase 2 hundreds of thousands each for therapy type of thing. The timing is very therapy dependent, right? This is not, this is not a slow strategy. The clinical trials can take, you know, 7, 10 years from start to finish. We're excited to be getting some towards that finish line for us, which is great. Each therapy has different endpoints, so we kind of map those, and that's why you can hear us in the prepared remarks talk about, you know, we do think we'll be supporting one by the end of 2027. That may be more as well, right? You know, it depends on their approvals, and the timings of those therapies. I think we're getting closer to that end. At the same time, on the front end, we're loading up the entire pipeline. I think as these things go through commercial, you'll probably start to see that average come up. Matt Hewett, Analyst, Craig-Hallum : That makes sense. Then you, it's a nice lead in there. Over the past, call it year, you've had the FDA and other agencies have come out either with draft guidance or more formal guidance. It really seems like the government is pushing to shorten that drug development time frame from the 10+ years historically to something much lower, whether it's on the front end with using AI and modeling or on the back end. They recently came out, it sounds like they're going to discontinue the need for phase 3 confirmatory studies, if you've got the right data. How does that shortening of the time frame, how does that kind of change your model, if at all? Is there anything that you can do to make sure that you're getting in on the very early end in what could be ultimately a shorter development process? Thank you. Stephen Gunstream, President and Chief Executive Officer, Teknova : Yeah, certainly, Matt. The shorter the time period is, the bigger impact it'll have on the business, right? We know that as they get through commercialization, there's a lot more spend there. That could be a really nice tailwind for the business generally. There are a number that we're supporting there, actually already phase 2, phase 3 combined, because they're either, you know, designated breakthrough or rare disease or both. Those are always really nice to see. We are fortunate in that, you know, many of these customers are already using us in the very early stages, right? Because of our capability to do these smaller batches, quickly of custom formulations. There's just not a lot of suppliers that can do that and then actually be compliant and scale all the way through commercialization. We do feel like we do feel good that we have a really strong position in that particular space. Certainly if the FDA does allow for these to be a shorter time periods, we would see a benefit there over time. Matt Hewett, Analyst, Craig-Hallum : That's great. Thank you. Operator : One moment for our next question. That will come from the line of Matthew Parisi with KeyBanc Capital Markets. Your line is open. Matthew Parisi, Analyst, KeyBanc Capital Markets : Hi, yes, this is Matthew Parisi on for Paul Knight at KeyBank. congrats on the quarter. just a quick question around cell and gene customers. What was the total number of cell and gene customers for 2025? Stephen Gunstream, President and Chief Executive Officer, Teknova : Good question, Matthew. I want to make sure I don't misquote this, but this is one we can get to you afterwards, and we'll put it out with a separate deck, I believe. Unless, Matt, you know it off the top of your head. Matt Hewett, Analyst, Craig-Hallum : Yeah, I don't know, but I will just say that maybe one other piece of information that would be helpful, which is that of our total revenue, 24% came from cell and gene therapy-related customers in 2025, which is not that different than in 2024, but that was the number for 2025. Maybe that's helpful. Matthew Parisi, Analyst, KeyBanc Capital Markets : Yeah, that's very helpful. Thank you. Matt Hewett, Analyst, Craig-Hallum : Okay. Operator : Thank you. That is all the time that we have for question and answers as well as today's conference call. This concludes today's program. Thank you all for participating. You may now disconnect. This article was generated with the support of AI and reviewed by an editor. For more information see our T&C. Is TKNO a bargain right now? The fastest way to find out is with our Fair Value calculator. We use a mix of 17 proven industry valuation models for maximum accuracy. Get the bottom line for TKNO plus thousands of other stocks and find your next hidden gem with massive upside.
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